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Mini-Reviews in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-193X
ISSN (Online): 1875-6298

Biotransformation of Terpenoids: A Green Alternative for Producing Molecules with Pharmacological Activity

Author(s): Y. Simeo and J. V. Sinisterra

Volume 6, Issue 2, 2009

Page: [128 - 134] Pages: 7

DOI: 10.2174/157019309788167710

Price: $65

Abstract

Terpenoids are natural products of great interest due to their broad application scope. They are employed as agrochemicals, drugs, fragrances, flavours and pigments. In the search of new derivatives with improved properties, the use of biocatalysts is being constantly increased, especially in redox processes. They can give rise to stereo- and regioselective products and/or compounds functionalized in remote positions difficult to reach by means of traditional organic chemistry. In this review, the application of whole cell catalyzed biotransformations of terpenoids to obtain new drug targets or to increase the pharmacological activity is presented.

Keywords: Terpenes, terpenoids, biotransformations, enzymes, redox process


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