Abstract
Alveolar capillary dysplasia (ACD) is a recently recognized lethal lung malformation. ACD is a rare congenital disorder of pulmonary vascular development associated with unremitting hypoxemia and respiratory failure. This paper reviews the incidence, pathophysiology and histopathology, clinical manifestations, diagnosis, and treatment of affected newborns and proposes an algorithmic approach to management of infants who present with unremitting persistent pulmonary hypertension of the newborn.
Keywords: Newborn, alveolar capillary dysplasia, pulmonary hypertension, extracorporeal membrane oxygenation
Current Respiratory Medicine Reviews
Title: Alveolar Capillary Dysplasia: A Lethal Developmental Lung Malformation
Volume: 5 Issue: 2
Author(s): Aaron W. Swenson and Steven M. Donn
Affiliation:
Keywords: Newborn, alveolar capillary dysplasia, pulmonary hypertension, extracorporeal membrane oxygenation
Abstract: Alveolar capillary dysplasia (ACD) is a recently recognized lethal lung malformation. ACD is a rare congenital disorder of pulmonary vascular development associated with unremitting hypoxemia and respiratory failure. This paper reviews the incidence, pathophysiology and histopathology, clinical manifestations, diagnosis, and treatment of affected newborns and proposes an algorithmic approach to management of infants who present with unremitting persistent pulmonary hypertension of the newborn.
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Cite this article as:
Swenson W. Aaron and Donn M. Steven, Alveolar Capillary Dysplasia: A Lethal Developmental Lung Malformation, Current Respiratory Medicine Reviews 2009; 5 (2) . https://dx.doi.org/10.2174/157339809788189950
DOI https://dx.doi.org/10.2174/157339809788189950 |
Print ISSN 1573-398X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6387 |
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