Abstract
Human Rhinoviruses (HRV) are by far the most common respiratory viruses responsible for most cases of the common cold and important pathogens in acute exacerbations of asthma and COPD. The molecular pathogenesis of HRV infection is quite completely understood. However there is still no approved specific treatment against HRV infections. The aim of this article is therefore to give an overview of the principles of rhinovirus infection, the associated therapeutic targets and to review up-to-date virus-specific clinical trials.
Keywords: Treatment, virus, airway, respiratory, antiviral, interferon, protease, capsid
Infectious Disorders - Drug Targets
Title: Drug Targets in Rhinoviral Infections
Volume: 9 Issue: 2
Author(s): Gernot Rohde
Affiliation:
Keywords: Treatment, virus, airway, respiratory, antiviral, interferon, protease, capsid
Abstract: Human Rhinoviruses (HRV) are by far the most common respiratory viruses responsible for most cases of the common cold and important pathogens in acute exacerbations of asthma and COPD. The molecular pathogenesis of HRV infection is quite completely understood. However there is still no approved specific treatment against HRV infections. The aim of this article is therefore to give an overview of the principles of rhinovirus infection, the associated therapeutic targets and to review up-to-date virus-specific clinical trials.
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Cite this article as:
Rohde Gernot, Drug Targets in Rhinoviral Infections, Infectious Disorders - Drug Targets 2009; 9 (2) . https://dx.doi.org/10.2174/187152609787847695
DOI https://dx.doi.org/10.2174/187152609787847695 |
Print ISSN 1871-5265 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3989 |
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