Application of Lanthanoid Catalysts for the Synthesis of Michlers Hydride

Title: Application of Lanthanoid Catalysts for the Synthesis of Michlers Hydride

Volume: 6 Issue: 3

Author(s): Philip C. Andrews, Peter C. Junk, K. Peter Kemppinen, Kristina Konstas and Kellie L. Tuck

Affiliation:

Keywords: Lanthanoids, Lewis acids, catalysis, radicals, oxidation

Abstract: A series of lanthanoid (Ln3+) based Lewis acid catalysts were investigated as alternatives to other metal based catalysts for the formation of Michlers hydride, 4,4-methylenebis(N,N-dimethylaniline) (1). The lanthanoid based Lewis acid catalysts were superior to previously published catalysts resulting in formation of 4,4-methylenebis(N,Ndimethylaniline) (1) and N,N-dimethyl-4-(4-(methylamino)benzyl)aniline (2). If paraformaldehyde was added to the reaction only 4,4-methylenebis(N,N-dimethylaniline) (1) was formed.

Cite this article as:

Andrews C. Philip, Junk C. Peter, Kemppinen Peter K., Konstas Kristina and Tuck L. Kellie, Application of Lanthanoid Catalysts for the Synthesis of Michlers Hydride, Letters in Organic Chemistry 2009; 6 (3) . https://dx.doi.org/10.2174/157017809787892993