Abstract
Chiral 3,4-difunctionalized pyrrolidines, which can be derived from L-(+)- and D-(-)-tartaric acids, are useful and versatile building blocks in total synthesis, catalyst preparation as well as supramolecular and medicinal chemistry. The preparation of these azacycles, possible transformations and their application are described herein.
Keywords: Tartaric Acids, C2-Symmetric Pyrrolidines, Chiral, Total Synthesis, Catalyst Design, Medicinal Chemistry
Current Organic Synthesis
Title: C2-Symmetric Pyrrolidines Derived from Tartaric Acids: Versatile Chiral Building Blocks for Total Synthesis, Catalyst Design, Supramolecular and Medicinal Chemistry
Volume: 6 Issue: 1
Author(s): Andreas Blum and Wibke E. Diederich
Affiliation:
Keywords: Tartaric Acids, C2-Symmetric Pyrrolidines, Chiral, Total Synthesis, Catalyst Design, Medicinal Chemistry
Abstract: Chiral 3,4-difunctionalized pyrrolidines, which can be derived from L-(+)- and D-(-)-tartaric acids, are useful and versatile building blocks in total synthesis, catalyst preparation as well as supramolecular and medicinal chemistry. The preparation of these azacycles, possible transformations and their application are described herein.
Export Options
About this article
Cite this article as:
Blum Andreas and Diederich E. Wibke, C2-Symmetric Pyrrolidines Derived from Tartaric Acids: Versatile Chiral Building Blocks for Total Synthesis, Catalyst Design, Supramolecular and Medicinal Chemistry, Current Organic Synthesis 2009; 6 (1) . https://dx.doi.org/10.2174/157017909787314902
DOI https://dx.doi.org/10.2174/157017909787314902 |
Print ISSN 1570-1794 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6271 |
Call for Papers in Thematic Issues
Exploring the Role of Chemical Graph Theory in Advancing Current Organic Synthesis
Organic synthesis is a fundamental discipline in chemistry, crucial for the creation of complex molecules with diverse applications in pharmaceuticals, materials science, and beyond. However, the process of designing efficient synthetic routes for target molecules remains challenging. Chemical graph theory, a branch of theoretical chemistry, offers powerful tools for understanding ...read more
Photoswitches for Molecular Recognition
This Special Issue would cover the hot topics on synthesis and chemical and photophysical characterization of new photoswitchable derivatives and their applications on molecular recognition of metabolites and biological active compounds, both in physiological medium and in living cells. Photoswitches are compounds that can change their conformation or properties in ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers