Abstract
Dysregulation of apoptosis is a major contributor to the initiation and aggravation of liver injury. Agents that modulate apoptosis may be of therapeutic benefit in a number of liver diseases, and research related to cell type-specific activation or inhibition of apoptotic signaling pathways will provide new strategies for treatment.
Keywords: Liver, hepatitis, alcohol, hepatocarcinoma, cholestasis, fulminant hepatic failure, steatohepatitis, fibrosis
Mini-Reviews in Medicinal Chemistry
Title: Apoptotic Signaling Pathways as a Target for the Treatment of Liver Diseases
Volume: 8 Issue: 14
Author(s): J. L. Mauriz, M. J. Tunon and J. Gonzalez-Gallego
Affiliation:
Keywords: Liver, hepatitis, alcohol, hepatocarcinoma, cholestasis, fulminant hepatic failure, steatohepatitis, fibrosis
Abstract: Dysregulation of apoptosis is a major contributor to the initiation and aggravation of liver injury. Agents that modulate apoptosis may be of therapeutic benefit in a number of liver diseases, and research related to cell type-specific activation or inhibition of apoptotic signaling pathways will provide new strategies for treatment.
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Cite this article as:
Mauriz L. J., Tunon J. M. and Gonzalez-Gallego J., Apoptotic Signaling Pathways as a Target for the Treatment of Liver Diseases, Mini-Reviews in Medicinal Chemistry 2008; 8 (14) . https://dx.doi.org/10.2174/138955708786786499
DOI https://dx.doi.org/10.2174/138955708786786499 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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