Abstract
Syntheses of diene based steroidal mimics of the estrogens, 2 and 3, were made through Wittig and McMurry reactions, as templates for estrogen receptor modulators.
Keywords: Template synthesis, Wittig reaction, McMurry reaction, steroids, drug research, receptors
Letters in Organic Chemistry
Title: Synthesis of Steroidal Mimics of Estrogens Using Wittig and McMurry Reactions
Volume: 5 Issue: 8
Author(s): Atul Gupta and Suprabhat Ray
Affiliation:
Keywords: Template synthesis, Wittig reaction, McMurry reaction, steroids, drug research, receptors
Abstract: Syntheses of diene based steroidal mimics of the estrogens, 2 and 3, were made through Wittig and McMurry reactions, as templates for estrogen receptor modulators.
Export Options
About this article
Cite this article as:
Gupta Atul and Ray Suprabhat, Synthesis of Steroidal Mimics of Estrogens Using Wittig and McMurry Reactions, Letters in Organic Chemistry 2008; 5 (8) . https://dx.doi.org/10.2174/157017808786857606
DOI https://dx.doi.org/10.2174/157017808786857606 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
New Perspectives on Acyl Glucuronide Risk Assessment in Drug Discovery: Investigation of In vitro Stability, In situ Reactivity, and Bioactivation
Drug Metabolism Letters Recent Advances in Predicting Protein Classification and Their Applications to Drug Development
Current Topics in Medicinal Chemistry Coumarins as Antioxidants
Current Medicinal Chemistry Resveratrol in Medicinal Chemistry: A Critical Review of its Pharmacokinetics, Drug-Delivery, and Membrane Interactions
Current Medicinal Chemistry Application in Electrochemistry of Graphene-Modified Electrodes
Micro and Nanosystems γ-AApeptides as a New Strategy for Therapeutic Development
Current Medicinal Chemistry Drug Targeting Systems for Cancer Therapy: Nanotechnological Approach
Mini-Reviews in Medicinal Chemistry T-Lymphocytes: A Target for Stimulatory and Inhibitory Effects of Zinc Ions
Endocrine, Metabolic & Immune Disorders - Drug Targets Capsaicin and Its Analogues: Structure-Activity Relationship Study
Current Medicinal Chemistry Harnessing Telomerase in Cancer Therapeutics
Anti-Cancer Agents in Medicinal Chemistry Virtual Screening of Natural Products to Select Compounds with Potential Anticancer Activity
Anti-Cancer Agents in Medicinal Chemistry Interaction of Drug or Food with Drug Transporters in Intestine and Liver
Current Drug Metabolism Doping and Genetic Testing: Sex Difference in UGT2B15 Expression, Testosterone Glucuronidation Activity and Urinary Testosterone/ Epitestosterone Glucuronide Ratio
Current Pharmacogenomics and Personalized Medicine Oral Administration of Thioflavin T Prevents Beta Amyloid Plaque Formation in Double Transgenic AD Mice
Current Alzheimer Research Potentials of Hydrogels in Cancer Therapy
Current Cancer Therapy Reviews Biomarkers of Oxidative Stress in the Assessment of Enantioselective Toxicity of Chiral Pesticides
Current Protein & Peptide Science Cyclodextrin Complexation of Meclizine Hydrochloride and its Influence on the Solubility for its Repurposing
Drug Delivery Letters Inhibitors of the HSP90 Molecular Chaperone: Attacking the Master Regulator in Cancer
Current Topics in Medicinal Chemistry A Sialic Acid-Specific Lectin from the Mushroom Paecilomyces Japonica that Exhibits Hemagglutination Activity and Cytotoxicity
Protein & Peptide Letters Proteostasis, an Emerging Therapeutic Paradigm for Managing Inflammatory Airway Stress Disease
Current Molecular Medicine