Abstract
Duchenne muscular dystrophy is the most common form of the childhood muscular dystrophies. It follows a predictable clinical course marked by progressive skeletal muscle weakness, lost of ambulation before teen- age and death in early adulthood secondary to respiratory or cardiac failure. Becker muscular dystrophy is less common and has a milder clinical course but also results in respiratory and cardiac failure. Female carriers of both entities are also affected in a variable degree. The natural history of the cardiac involvement in these diseases has not been well established and without screening it progresses asymptomatically until the cardiac reserve has been eroded, when symptoms and signs of cardiac failure emerge. The purpose of this work is to provide recommendations for adequate cardiovascular care in this particular population based on the updated literature as referenced.
Keywords: Neuromuscular diseases, Duchenne muscular dystrophy, Becker muscular dystrophy, cardiovascular care
Current Pediatric Reviews
Title: Cardiovascular Surveillance of Duchenne and Becker Muscular Dystrophy and Female Carriers
Volume: 4 Issue: 3
Author(s): Virginia Spehrs-Ciaffi, Pierre-Yves Jeannet and Nicole Sekarski
Affiliation:
Keywords: Neuromuscular diseases, Duchenne muscular dystrophy, Becker muscular dystrophy, cardiovascular care
Abstract: Duchenne muscular dystrophy is the most common form of the childhood muscular dystrophies. It follows a predictable clinical course marked by progressive skeletal muscle weakness, lost of ambulation before teen- age and death in early adulthood secondary to respiratory or cardiac failure. Becker muscular dystrophy is less common and has a milder clinical course but also results in respiratory and cardiac failure. Female carriers of both entities are also affected in a variable degree. The natural history of the cardiac involvement in these diseases has not been well established and without screening it progresses asymptomatically until the cardiac reserve has been eroded, when symptoms and signs of cardiac failure emerge. The purpose of this work is to provide recommendations for adequate cardiovascular care in this particular population based on the updated literature as referenced.
Export Options
About this article
Cite this article as:
Spehrs-Ciaffi Virginia, Jeannet Pierre-Yves and Sekarski Nicole, Cardiovascular Surveillance of Duchenne and Becker Muscular Dystrophy and Female Carriers, Current Pediatric Reviews 2008; 4 (3) . https://dx.doi.org/10.2174/157339608785856027
DOI https://dx.doi.org/10.2174/157339608785856027 |
Print ISSN 1573-3963 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6336 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Why is the Inhibition of the Renin-Angiotensin System Effective for Preventing Cardiac Events in Patients with Coronary Risk Factors or Coronary Artery Disease?
Current Cardiology Reviews Principles and Therapeutic Relevance for Targeting Mitochondria in Aging and Neurodegenerative Diseases
Current Pharmaceutical Design Cardiovascular Proteomics
Current Proteomics The Rationale for Comparative Studies of Accelerated Atherosclerosis in Rheumatic Diseases
Current Vascular Pharmacology Neopterin: From Forgotten Biomarker to Leading Actor in Cardiovascular Pathophysiology
Current Vascular Pharmacology Nuclear Imaging of Post-infarction Inflammation in Ischemic Cardiac Diseases - New Radiotracers for Potential Clinical Applications
Current Radiopharmaceuticals EDITORIAL [Hot Topic: Diabetes Cardiovascular Complications (Guest Editor: Costanza Emanueli)]
Endocrine, Metabolic & Immune Disorders - Drug Targets Evaluation of the Antioxidant and Antidiabetic Potential of the Poly Herbal Formulation: Identification of Bioactive Factors
Cardiovascular & Hematological Agents in Medicinal Chemistry Thymosin β4 Protein Therapy for Cardiac Repair
Current Pharmaceutical Design Mitochondrial Toxicity in HAART: An Overview of In Vitro Evidence
Current Pharmaceutical Design A Review of the Pharmacological Properties of 3,4-dihydro-2(1H)- quinolinones
Mini-Reviews in Medicinal Chemistry Immunomodulatory Roles of VIP and PACAP in Models of Multiple Sclerosis
Current Pharmaceutical Design Potential Therapeutic Benefits of Sodium-Glucose Cotransporter 2 Inhibitors in the Context of Ischemic Heart Failure: A State-of-the-Art Review
Cardiovascular & Hematological Agents in Medicinal Chemistry Restoration of Cardiomyocyte Function in Streptozotocin-Induced Diabetic Rats after Treatment with Vanadate in a Tea Decoction
Current Pharmaceutical Biotechnology Sexual Dysfunction in Men and Women with Diabetes: A Reflection of their Complications?
Current Diabetes Reviews The Role of AGEs and AGE Inhibitors in Diabetic Cardiovascular Disease
Current Drug Targets Muscular Dystrophies: Histology, Immunohistochemistry, Molecular Genetics and Management
Current Pharmaceutical Design Pleiotropic Effects of Statin in Therapy in Heart Failure: A Review
Current Vascular Pharmacology 5-Adenosine Monophosphate-Activated Protein Kinase and the Metabolic Syndrome
Endocrine, Metabolic & Immune Disorders - Drug Targets Homocysteine and Heart Failure: An Overview
Recent Patents on Cardiovascular Drug Discovery