Abstract
Dendrimers as a new kind of polymer have been studied for medical applications mainly in two aspects: drug delivery and gene delivery. The unique characteristics, such as uniformity, monodispersity and the ability to functionalize their terminal groups with various targeting agents distinguish them as versatile carriers. In the paper the recent advances of dendrimer in gene transfer vehicles and drug delivery are separately reviewed. These advances illustrate the direction of the future development of dendrimers.
Keywords: Dendrimer, delivery of dene, delivery of drug, DNA/RNA, PAMAM, PEI, PPI
Mini-Reviews in Medicinal Chemistry
Title: Recent Advances of Dendrimers in Delivery of Genes and Drugs
Volume: 8 Issue: 9
Author(s): Yu Gao, Ge Gao, Yun He, Taole Liu and Rong Qi
Affiliation:
Keywords: Dendrimer, delivery of dene, delivery of drug, DNA/RNA, PAMAM, PEI, PPI
Abstract: Dendrimers as a new kind of polymer have been studied for medical applications mainly in two aspects: drug delivery and gene delivery. The unique characteristics, such as uniformity, monodispersity and the ability to functionalize their terminal groups with various targeting agents distinguish them as versatile carriers. In the paper the recent advances of dendrimer in gene transfer vehicles and drug delivery are separately reviewed. These advances illustrate the direction of the future development of dendrimers.
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Cite this article as:
Gao Yu, Gao Ge, He Yun, Liu Taole and Qi Rong, Recent Advances of Dendrimers in Delivery of Genes and Drugs, Mini-Reviews in Medicinal Chemistry 2008; 8 (9) . https://dx.doi.org/10.2174/138955708785132729
DOI https://dx.doi.org/10.2174/138955708785132729 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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