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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Electrophilic Substitution Reaction of Indole: Part XXII-Synthesis of a Novel Spiro Heterocyclic System

Author(s): Anupam Nayak, Asima Chatterjee, Julie Banerji, Munmun Saha, Sukumar Manna, Sanchayita Kanrar and Tomoyasu Hirose

Volume 5, Issue 5, 2008

Page: [403 - 406] Pages: 4

DOI: 10.2174/157017808784872070

Price: $65

Abstract

The reaction of indole with acetone in the presence of mineral/Lewis acid continues to be a fascinating area for investigation since 1913, specially due to the instability of the indolyl carbinol being generated in situ. We report here the synthesis of a novel spiro heterocyclic system obtained during the study of this reaction using BF3.Et2O.

Keywords: Indole, acetone, spiro system, X-ray crystallography

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