Synthesis and Biological Evaluation of a New Series of Benzothiazole-Quinolone Hybrids as Antibacterial Agents

Title: Synthesis and Biological Evaluation of a New Series of Benzothiazole-Quinolone Hybrids as Antibacterial Agents

Volume: 5 Issue: 5

Author(s): Ahmed Kamal, S. Kaleem Ahmed, M. Naseer A. Khan, Rajesh V.C.R.N.C. Shetty, B. Siddhardha and U. S.N. Murty

Affiliation:

Keywords: Benzothiazoles, Quinolones, Antibacterial activity

Abstract: In an effort to develop new and more effective therapies to treat bacterial infection, quinolone coupled benzothiazoles (6a-f) have prepared and evaluated for their efficacy as antibacterial agents against various Gram-positive and Gram-negative strains of bacteria. Some of the compounds from this series exhibited antibacterial activity comparable to ciprofloxacin.

Cite this article as:

Kamal Ahmed, Ahmed Kaleem S., A. Khan Naseer M., Shetty V.C.R.N.C. Rajesh, Siddhardha B. and Murty S.N. U., Synthesis and Biological Evaluation of a New Series of Benzothiazole-Quinolone Hybrids as Antibacterial Agents, Letters in Drug Design & Discovery 2008; 5 (5) . https://dx.doi.org/10.2174/157018008784912072