Antibacterial Pleuromutilin Derivatives based on Alternate Core Structures:Arigoni and Birch Chemistry Revisited

Title: Antibacterial Pleuromutilin Derivatives based on Alternate Core Structures:Arigoni and Birch Chemistry Revisited

Volume: 5 Issue: 5

Author(s): Dane M. Springer, Jason T. Goodrich, Bing-Yu Luh, Joanne J. Bronson, Qi Gao, Stella Huang, Kenneth DenBleyker, Thomas J. Dougherty and Joan Fung-Tomc

Affiliation:

Abstract: Pleuromutilin derivatives comprised of varied core structures have been synthesized. Many of the compounds described were found to have surprisingly good antibacterial activity in vitro.

Cite this article as:

Springer M. Dane, Goodrich T. Jason, Luh Bing-Yu, Bronson J. Joanne, Gao Qi, Huang Stella, DenBleyker Kenneth, Dougherty J. Thomas and Fung-Tomc Joan, Antibacterial Pleuromutilin Derivatives based on Alternate Core Structures:Arigoni and Birch Chemistry Revisited, Letters in Drug Design & Discovery 2008; 5 (5) . https://dx.doi.org/10.2174/157018008784912063