Abstract
Beta-amyloid (Aβ) likely plays a pivotal role in the etiology of Alzheimers disease (AD). Consequently, Aβ-associated pathways are targets for the development of possible effective AD therapies. This review first updates strategies aimed at the inhibition of Aβ formation and then discusses the role of food-derived polyphenols as putative antiamyloid drugs.
Keywords: Alzheimer's disease, polyphenols, neuroprotection
Mini-Reviews in Medicinal Chemistry
Title: Polyphenols as Potential Inhibitors of Amyloid Aggregation and Toxicity:Possible Significance to Alzheimers Disease
Volume: 8 Issue: 5
Author(s): S. Bastianetto, S. Krantic and R. Quirion
Affiliation:
Keywords: Alzheimer's disease, polyphenols, neuroprotection
Abstract: Beta-amyloid (Aβ) likely plays a pivotal role in the etiology of Alzheimers disease (AD). Consequently, Aβ-associated pathways are targets for the development of possible effective AD therapies. This review first updates strategies aimed at the inhibition of Aβ formation and then discusses the role of food-derived polyphenols as putative antiamyloid drugs.
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Bastianetto S., Krantic S. and Quirion R., Polyphenols as Potential Inhibitors of Amyloid Aggregation and Toxicity:Possible Significance to Alzheimers Disease, Mini-Reviews in Medicinal Chemistry 2008; 8 (5) . https://dx.doi.org/10.2174/138955708784223512
DOI https://dx.doi.org/10.2174/138955708784223512 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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