Abstract
We review studies examining the impact of obesity on survival, morbidity, and respiratory failure in critical illness. Given the increasing rates of overweight and obesity, there is a surprising lack of well-conducted clinical trials addressing its interaction with critical illness. Unexpectedly, it seems that obesity may not negatively impact, or may even be protective with regards to mortality, though there are a few studies that support conventional wisdom, demonstrating worsened outcomes amongst the obese. Being obese does seem to predispose to respiratory failure, given altered lung and chest wall mechanics, and increased metabolic demands, though it is uncertain how it might impact survival in patients requiring ventilatory support.
Current Respiratory Medicine Reviews
Title: Critical Illness in the Obese Patient
Volume: 4 Issue: 2
Author(s): Steven Y. Chang, John P. Kress and Jesse B. Hall
Affiliation:
Abstract: We review studies examining the impact of obesity on survival, morbidity, and respiratory failure in critical illness. Given the increasing rates of overweight and obesity, there is a surprising lack of well-conducted clinical trials addressing its interaction with critical illness. Unexpectedly, it seems that obesity may not negatively impact, or may even be protective with regards to mortality, though there are a few studies that support conventional wisdom, demonstrating worsened outcomes amongst the obese. Being obese does seem to predispose to respiratory failure, given altered lung and chest wall mechanics, and increased metabolic demands, though it is uncertain how it might impact survival in patients requiring ventilatory support.
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Cite this article as:
Chang Y. Steven, Kress P. John and Hall B. Jesse, Critical Illness in the Obese Patient, Current Respiratory Medicine Reviews 2008; 4 (2) . https://dx.doi.org/10.2174/157339808784222605
DOI https://dx.doi.org/10.2174/157339808784222605 |
Print ISSN 1573-398X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6387 |
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