Abstract
Antioxidant potential of nineteen imidazolones derivatives has been evaluated and their structure-activity relationships established. A rapid and efficient synthesis of imidazolylbenamides was achieved from different azalactones (oxazolones) by reacting with phenyl hydrazide in basic media under microwave irradiation. Excellent yields, high purity, short reaction time and easy and simple work-up are the main features of this synthesis.
Keywords: Microwave-assisted synthesis, Imidazolylbenzamides, Antioxidant, Nitric Oxide
Letters in Drug Design & Discovery
Title: Microwaves-Assisted Syntheses of Imidazolylbenzamides and their Antioxidant Activities
Volume: 5 Issue: 3
Author(s): Khalid Mohammed Khan, Uzma Rasool Mughal, Iman Omar and M. Iqbal Choudhary
Affiliation:
Keywords: Microwave-assisted synthesis, Imidazolylbenzamides, Antioxidant, Nitric Oxide
Abstract: Antioxidant potential of nineteen imidazolones derivatives has been evaluated and their structure-activity relationships established. A rapid and efficient synthesis of imidazolylbenamides was achieved from different azalactones (oxazolones) by reacting with phenyl hydrazide in basic media under microwave irradiation. Excellent yields, high purity, short reaction time and easy and simple work-up are the main features of this synthesis.
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Cite this article as:
Khan Mohammed Khalid, Mughal Rasool Uzma, Omar Iman and Choudhary Iqbal M., Microwaves-Assisted Syntheses of Imidazolylbenzamides and their Antioxidant Activities, Letters in Drug Design & Discovery 2008; 5 (3) . https://dx.doi.org/10.2174/157018008784083974
DOI https://dx.doi.org/10.2174/157018008784083974 |
Print ISSN 1570-1808 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-628X |
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