Abstract
A series of β-aminosulfones were synthesized with high enantioselectivities via a new approach, which combines asymmetric hydrogenation of β-ketosulfones and Mitsunobu amination reaction of the corresponding β- hydroxysulfones with a significant high control of the stereochemistry.
Keywords: Catalysts, ruthenium, asymmetric hydrogenation, β-hydroxysulfones, Mitsunobu amination, β-aminosulfones
Letters in Organic Chemistry
Title: Asymmetric Synthesis of β-Aminosulfones Via the Enantioselective Hydrogenation of the Corresponding β-Ketosulfones
Volume: 5 Issue: 3
Author(s): Ridha Touati and Bechir Ben Hassine
Affiliation:
Keywords: Catalysts, ruthenium, asymmetric hydrogenation, β-hydroxysulfones, Mitsunobu amination, β-aminosulfones
Abstract: A series of β-aminosulfones were synthesized with high enantioselectivities via a new approach, which combines asymmetric hydrogenation of β-ketosulfones and Mitsunobu amination reaction of the corresponding β- hydroxysulfones with a significant high control of the stereochemistry.
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Cite this article as:
Touati Ridha and Hassine Ben Bechir, Asymmetric Synthesis of β-Aminosulfones Via the Enantioselective Hydrogenation of the Corresponding β-Ketosulfones, Letters in Organic Chemistry 2008; 5 (3) . https://dx.doi.org/10.2174/157017808783955835
DOI https://dx.doi.org/10.2174/157017808783955835 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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