Abstract
In celiac disease (CD), abnormal immune-mediated responses follow ingestion of gluten. Although the triggering agent is a dietary protein, the disease has autoimmune components because of the presence of autoantibodies and its association with autoimmune conditions. We review the most recent studies on CD pathogenesis and the possibilities to modulate immune dysfunction in CD.
Keywords: epidermal growth factor, glutenins, anti-endomysium antibodies, tissue transglutaminase type II, prolyl endopeptidases
Mini-Reviews in Medicinal Chemistry
Title: Autoimmunity and Celiac Disease
Volume: 8 Issue: 2
Author(s): Antonio La Cava, Carmen Gianfrani and Riccardo Troncone
Affiliation:
Keywords: epidermal growth factor, glutenins, anti-endomysium antibodies, tissue transglutaminase type II, prolyl endopeptidases
Abstract: In celiac disease (CD), abnormal immune-mediated responses follow ingestion of gluten. Although the triggering agent is a dietary protein, the disease has autoimmune components because of the presence of autoantibodies and its association with autoimmune conditions. We review the most recent studies on CD pathogenesis and the possibilities to modulate immune dysfunction in CD.
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Cite this article as:
Cava La Antonio, Gianfrani Carmen and Troncone Riccardo, Autoimmunity and Celiac Disease, Mini-Reviews in Medicinal Chemistry 2008; 8 (2) . https://dx.doi.org/10.2174/138955708783498113
DOI https://dx.doi.org/10.2174/138955708783498113 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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