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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Excellent Exo/Endo-Selectivity in the 1,3-Dipolar Cycloaddition of Cyclic Azomethine Ylide: Exploring the Facile Investigation of Cocaine Antagonists

Author(s): Joydev K. Laha

Volume 4, Issue 8, 2007

Page: [550 - 552] Pages: 3

DOI: 10.2174/157017807782795448

Price: $65

Abstract

High exo-selectivity was achieved in the 1,3-dipolar cycloaddition of a cyclic azomethine ylide and phenyl vinyl sulfone or Opplozers camphorsultam chiral dipolarophile leading to the synthesis of two novel tropane compounds.

Keywords: Cocaine antagonists, tropane, 1,3-dipolar cycloaddition, cyclic azomethine ylide, exo/endo-selectivity


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