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Current Rheumatology Reviews

Editor-in-Chief

ISSN (Print): 1573-3971
ISSN (Online): 1875-6360

Pyridinoline, A Collagen Crosslink, As a Biochemical Marker for Arthritis

Author(s): Masaaki Takahashi

Volume 3, Issue 4, 2007

Page: [252 - 260] Pages: 9

DOI: 10.2174/157339707782409017

Price: $65

Abstract

Pyridinoline is a crosslink synthesized in collagen that has generally been used as a biochemical marker for bone metabolism. In addition, as pyridinoline is more abundant in cartilage and synovium than in the other tissues, there is extensive literature describing pyridinoline as a biochemical marker for cartilage destruction and metabolism, or arthritis. This paper will review the use of pyridinoline as a biochemical marker for arthritis.

Keywords: Deoxypyridinoline, urinary pyridinoline, Collagen, osteoarthritis, Ankylosing Spondylitis


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