Abstract
It is suggested that the interactions between the hydrophobic C-H groups of carbohydrate residues and the p-electron systems of aromatic amino-acid residues play an important role in the ligand-recognition function of carbohydrate-binding proteins. This review focuses on our recent structural and functional studies of human lysozyme and hevein-domain type lectins (wheat-germ agglutinin and Ac-AMP2) aimed at understanding how CH / π interactions are involved in the actual binding events.
Keywords: interaction, carbohydrate binding protein, cbp interaction
Protein & Peptide Letters
Title: The Importance of Ch / π Interactions to the Function of Carbohydrate Binding Proteins
Volume: 9 Issue: 3
Author(s): Michiro Muraki
Affiliation:
Keywords: interaction, carbohydrate binding protein, cbp interaction
Abstract: It is suggested that the interactions between the hydrophobic C-H groups of carbohydrate residues and the p-electron systems of aromatic amino-acid residues play an important role in the ligand-recognition function of carbohydrate-binding proteins. This review focuses on our recent structural and functional studies of human lysozyme and hevein-domain type lectins (wheat-germ agglutinin and Ac-AMP2) aimed at understanding how CH / π interactions are involved in the actual binding events.
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Cite this article as:
Muraki Michiro, The Importance of Ch / π Interactions to the Function of Carbohydrate Binding Proteins, Protein & Peptide Letters 2002; 9 (3) . https://dx.doi.org/10.2174/0929866023408751
DOI https://dx.doi.org/10.2174/0929866023408751 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |
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