Abstract
The plant-derived terpenoids and analogues are reviewed with respect to their anti-HIV activity, structure-activity relationships, and mechanism of action. The active compounds include diterpenoid lactones, phenolic diterpenes, atisane and kaurane diterpenes, phorbol diterpenes, triterpene glycosides, friedelane triterpenes, taraxerane triterpenes, ursane triterpenes, lanostane triterpene, lupane triterpenes, seco-ring A triterpenes, degraded triterpenes, and cucurbitacin triterpenes. Positive new leads for drug development will be highlighted.
Keywords: Terpenoids, lanostane, triterpene glycosides, ursane, lupane triterpenes, cucurbitacin, taraxerane
Current Topics in Medicinal Chemistry
Title: Plant-derived Terpenoids and Analogues as Anti-HIV Agents
Volume: 3 Issue: 2
Author(s): Kuo-Hsiung Lee
Affiliation:
Keywords: Terpenoids, lanostane, triterpene glycosides, ursane, lupane triterpenes, cucurbitacin, taraxerane
Abstract: The plant-derived terpenoids and analogues are reviewed with respect to their anti-HIV activity, structure-activity relationships, and mechanism of action. The active compounds include diterpenoid lactones, phenolic diterpenes, atisane and kaurane diterpenes, phorbol diterpenes, triterpene glycosides, friedelane triterpenes, taraxerane triterpenes, ursane triterpenes, lanostane triterpene, lupane triterpenes, seco-ring A triterpenes, degraded triterpenes, and cucurbitacin triterpenes. Positive new leads for drug development will be highlighted.
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Cite this article as:
Lee Kuo-Hsiung, Plant-derived Terpenoids and Analogues as Anti-HIV Agents, Current Topics in Medicinal Chemistry 2003; 3 (2) . https://dx.doi.org/10.2174/1568026033392435
DOI https://dx.doi.org/10.2174/1568026033392435 |
Print ISSN 1568-0266 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4294 |
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