Abstract
Peptide-based enzyme-linked immunosorbent assays have been found to be enough sensitive and specific for the diagnosis of human immunodeficiency virus specific antibodies in acquired immunodeficiency syndrome patients. This review provides an overview of the most important peptides developed for use as synthetic antigens in immunodiagnosis of HIV-infected patients. In particular, many studies have been devoted to discriminate between the two retroviruses HIV-1 and HIV-2, as well as different subtypes.
Keywords: synthetic peptides, neurological diseases, commercially-available assays, prion diseases, diagnostic methodologies, autoimmune disease
Current Protein & Peptide Science
Title: Synthetic Peptides in the Diagnosis of HIV Infection
Volume: 4 Issue: 4
Author(s): Maria Claudia Alcaro, Elisa Peroni, Paolo Rovero and Anna Maria Papini
Affiliation:
Keywords: synthetic peptides, neurological diseases, commercially-available assays, prion diseases, diagnostic methodologies, autoimmune disease
Abstract: Peptide-based enzyme-linked immunosorbent assays have been found to be enough sensitive and specific for the diagnosis of human immunodeficiency virus specific antibodies in acquired immunodeficiency syndrome patients. This review provides an overview of the most important peptides developed for use as synthetic antigens in immunodiagnosis of HIV-infected patients. In particular, many studies have been devoted to discriminate between the two retroviruses HIV-1 and HIV-2, as well as different subtypes.
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Cite this article as:
Alcaro Claudia Maria, Peroni Elisa, Rovero Paolo and Papini Maria Anna, Synthetic Peptides in the Diagnosis of HIV Infection, Current Protein & Peptide Science 2003; 4 (4) . https://dx.doi.org/10.2174/1389203033487117
DOI https://dx.doi.org/10.2174/1389203033487117 |
Print ISSN 1389-2037 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5550 |
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