Isoquinoline Alkaloids from Duguetia Vallicola Stem Bark with Antiplasmodial Activity

Title: Isoquinoline Alkaloids from Duguetia Vallicola Stem Bark with Antiplasmodial Activity

Volume: 1 Issue: 1

Author(s): E. Perez, J. Saez, S. Blair, X. Franck and B. Figadere

Affiliation:

Keywords: isoquinoline alkaloids, duguetia vallicola, annonaceae, antiplasmodial

Abstract: Duguevalline (1), a novel aporphinoid alkaloid, in addition to four known alkaloids, cleistopholine (2), O-methylmoschatoline (3), (-)-oliveroline (4) and (-)-oliveridine (5), were isolated and characterized from Duguetia vallicola stems. Structural elucidation of these compounds was established by spectroscopic methods. Among them, alkaloids (2) and (4) exhibited antiplasmodial activity against Plasmodium falciparum.

Cite this article as:

Perez E., Saez J., Blair S., Franck X. and Figadere B., Isoquinoline Alkaloids from Duguetia Vallicola Stem Bark with Antiplasmodial Activity, Letters in Organic Chemistry 2004; 1 (1) . https://dx.doi.org/10.2174/1570178043488743