Modulation of the Arachidonic Cascade with ω3 Fatty Acids or Analogues: Potential Therapeutic Benefits

Title: Modulation of the Arachidonic Cascade with ω3 Fatty Acids or Analogues: Potential Therapeutic Benefits

Volume: 4 Issue: 6

Author(s): Isabelle Roland, Xavier de Leval, Brigitte Evrard, Bernard Pirotte, Jean-Michel Dogne and Luc Delattre

Affiliation:

Keywords: fatty acid, ratio, cardiovascular disease, cancer, inflammation, psychiatric disorders

Abstract: Increasing interest in the role of ω3 fatty acids has arisen in these latest years since evidence of their implication in the cardioprotective fish based diet of the Inuit has been demonstrated. Furthermore, several in vitro, in vivo and epidemiological studies support the benefit of this fatty acids intake in various pathological states such as in the cardiovascular, cancer, inflammation, psychiatric, paediatric, pulmonary, dermatological and ophthalmologic fields. This review will focus on metabolism and pharmacological implication of ω3 fatty acids intake as well as its interest in the prevention or treatment of the above-mentioned pathologies.

Cite this article as:

Roland Isabelle, Leval de Xavier, Evrard Brigitte, Pirotte Bernard, Dogne Jean-Michel and Delattre Luc, Modulation of the Arachidonic Cascade with ω3 Fatty Acids or Analogues: Potential Therapeutic Benefits, Mini-Reviews in Medicinal Chemistry 2004; 4 (6) . https://dx.doi.org/10.2174/1389557043403738