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Current Vascular Pharmacology

Editor-in-Chief

ISSN (Print): 1570-1611
ISSN (Online): 1875-6212

Cardiovascular Toxicity from the Perspective of Oxidative Stress, Electron Transfer, and Prevention by Antioxidants

Author(s): Peter Kovacic and Lisa A. Thurn

Volume 3, Issue 2, 2005

Page: [107 - 117] Pages: 11

DOI: 10.2174/1570161053586912

Price: $65

Abstract

This review demonstrates that oxidative stress, reactive oxygen species, and electron transfer can serve as unifying mechanistic themes for large numbers of cardiovascular toxins, both endogenous and exogenous. Lipid peroxidation is a prevalent insult. Common among the various conditions are atherosclerosis and arrhythmia. The preventive effects of antioxidants are documented.

Keywords: cardiovascular toxins, oxidative stress, electron transfer, lipoperoxidation, antioxidants, reactive oxygen species, radicals

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