Abstract
An improved synthesis of DC-Cholesterol, its analogues and Vitamin D-based lipids for the preparation of liposomes in gene therapy, is described. This synthetic strategy affords significative increase in the yields of DC-Cholesterol and its analogs.
Keywords: cationic lipids, gene therapy, dc-cholesterol, modified curtius reaction, dc-vitamin d-based cationic lipids
Letters in Organic Chemistry
Title: A Simple Approach to DC-Cholesterol, its Analogues and Vitamin D-Based Cationic Lipids for Gene Therapy
Volume: 2 Issue: 1
Author(s): Armandodoriano Bianco, Francesco Bonadies, Raffaella Napolitano and Giancarlo Ortaggi
Affiliation:
Keywords: cationic lipids, gene therapy, dc-cholesterol, modified curtius reaction, dc-vitamin d-based cationic lipids
Abstract: An improved synthesis of DC-Cholesterol, its analogues and Vitamin D-based lipids for the preparation of liposomes in gene therapy, is described. This synthetic strategy affords significative increase in the yields of DC-Cholesterol and its analogs.
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Cite this article as:
Bianco Armandodoriano, Bonadies Francesco, Napolitano Raffaella and Ortaggi Giancarlo, A Simple Approach to DC-Cholesterol, its Analogues and Vitamin D-Based Cationic Lipids for Gene Therapy, Letters in Organic Chemistry 2005; 2 (1) . https://dx.doi.org/10.2174/1570178053399921
DOI https://dx.doi.org/10.2174/1570178053399921 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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