Synthesis and Characterization of a Novel Protein Tyrosine Phosphatase Inhibitor, 2-(Cyclobutylamino)- N- (2-Furylmethyl)-2-Thioxoacetamide

Title: Synthesis and Characterization of a Novel Protein Tyrosine Phosphatase Inhibitor, 2-(Cyclobutylamino)- N- (2-Furylmethyl)-2-Thioxoacetamide

Volume: 2 Issue: 3

Author(s): Y. Kobayashi-Matsunaga, T. Ishii, T. Hamaguchi, H. Osada and M. Sato

Affiliation:

Keywords: protein tyrosine phosphatase inhibitor, cd, thioxoacetamide

Abstract: The synthesis and biological activities of a series of 2-amino-2-thioxoacetamide derivatives are described. These compounds have inhibitory effects against the protein tyrosine phosphatase activity of CD45. Compound 4i inhibited the PCA reaction in vivo.

Cite this article as:

Kobayashi-Matsunaga Y., Ishii T., Hamaguchi T., Osada H. and Sato M., Synthesis and Characterization of a Novel Protein Tyrosine Phosphatase Inhibitor, 2-(Cyclobutylamino)- N- (2-Furylmethyl)-2-Thioxoacetamide, Letters in Drug Design & Discovery 2005; 2 (3) . https://dx.doi.org/10.2174/1570180053765101