Recent Advances in Microwave-Assisted Synthesis of Heterocyclic Compounds

Title: Recent Advances in Microwave-Assisted Synthesis of Heterocyclic Compounds

Volume: 2 Issue: 3

Author(s): Valentina Molteni and David A. Ellis

Affiliation:

Keywords: microwave technology, acylation, deprotection, cycloaddition, polarization, single-mode reactors, isoxazolidines, indolizines, diels-alder reaction, thiiranes

Abstract: Heterocyclic scaffolds represent the central framework of many biologically active compounds. The goal of this review is to present advances in the field of microwave-assisted synthesis of heterocyclic compounds that have been described in the literature since 1994. In particular, it focuses on reactions in which a heteroatom is directly participating in the bond forming process that gives rise to a heterocyclic core. The review is divided into two sections, cycloaddition and cyclization reactions, which are further classified according to ring type. These reactions are discussed from a synthetic standpoint with emphasis on comparison between microwave and conventional techniques.

Cite this article as:

Molteni Valentina and Ellis A. David, Recent Advances in Microwave-Assisted Synthesis of Heterocyclic Compounds, Current Organic Synthesis 2005; 2 (3) . https://dx.doi.org/10.2174/1570179054368518