Abstract
Michael Laskowski Jr. (1930-2004) was a pioneer in the field of Standard mechanism serine proteinase inhibitors. He made numerous important contributions in the field. This article highlights some of his most important contributions such as the discovery of the reactive site in serine proteinase inhibitors, the proposal of the Standard mechanism of inhibition, and the sequence to reactivity algorithm for the Kazal family of inhibitors.
Keywords: proteinase inhibitors, spectroscopy, thermodynamics, reactive site residue, chymotrypsin
Protein & Peptide Letters
Title: From the Discovery of the Reactive Site of Inhibitors to Their Sequence to Reactivity Algorithm
Volume: 12 Issue: 5
Author(s): M. A. Qasim
Affiliation:
Keywords: proteinase inhibitors, spectroscopy, thermodynamics, reactive site residue, chymotrypsin
Abstract: Michael Laskowski Jr. (1930-2004) was a pioneer in the field of Standard mechanism serine proteinase inhibitors. He made numerous important contributions in the field. This article highlights some of his most important contributions such as the discovery of the reactive site in serine proteinase inhibitors, the proposal of the Standard mechanism of inhibition, and the sequence to reactivity algorithm for the Kazal family of inhibitors.
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Cite this article as:
Qasim A. M., From the Discovery of the Reactive Site of Inhibitors to Their Sequence to Reactivity Algorithm, Protein & Peptide Letters 2005; 12 (5) . https://dx.doi.org/10.2174/0929866054395347
DOI https://dx.doi.org/10.2174/0929866054395347 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |
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