Enantioselective Nozaki-Hiyama Allylations Using a Multidentate Amino Alcohol as a Chiral Ligand

Title: Enantioselective Nozaki-Hiyama Allylations Using a Multidentate Amino Alcohol as a Chiral Ligand

Volume: 2 Issue: 6

Author(s): E. Rozners and J. Fontanez

Affiliation:

Keywords: chromium, asymmetric reaction, aldehydes, homoallylic alcohols

Abstract: Asymmetric Nozaki-Hiyama allylations using a proline derived amino alcohol as a chiral ligand showed good enantioselectivity (er up to 90:10). The results suggest that efficient catalysts for this type of chromium-mediated reactions may be designed using multidentate ligands based on sp3 hybridized backbones.

Cite this article as:

Rozners E. and Fontanez J., Enantioselective Nozaki-Hiyama Allylations Using a Multidentate Amino Alcohol as a Chiral Ligand, Letters in Organic Chemistry 2005; 2 (6) . https://dx.doi.org/10.2174/1570178054640877