Abstract
Antimicrobial peptides are present in organisms spanning virtually every kingdom, and employ sophisticated mechanisms to exert rapid microbicidal action consistent with their key roles in host defense. Offsetting these mechanisms, some microbial pathogens have evolved complex countermeasures to neutralize exposure to and subvert mechanisms of antimicrobial peptides. The following discussion highlights recent advances that offer greater understanding of the mechanisms of action and resistance of antimicrobial peptides.
Keywords: antimicrobial, peptide, resistance, mechanism
Protein & Peptide Letters
Title: Immunocontinuum: Perspectives in Antimicrobial Peptide Mechanisms of Action and Resistance
Volume: 12 Issue: 1
Author(s): Nannette Y. Yount and Michael R. Yeaman
Affiliation:
Keywords: antimicrobial, peptide, resistance, mechanism
Abstract: Antimicrobial peptides are present in organisms spanning virtually every kingdom, and employ sophisticated mechanisms to exert rapid microbicidal action consistent with their key roles in host defense. Offsetting these mechanisms, some microbial pathogens have evolved complex countermeasures to neutralize exposure to and subvert mechanisms of antimicrobial peptides. The following discussion highlights recent advances that offer greater understanding of the mechanisms of action and resistance of antimicrobial peptides.
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Cite this article as:
Yount Y. Nannette and Yeaman R. Michael, Immunocontinuum: Perspectives in Antimicrobial Peptide Mechanisms of Action and Resistance, Protein & Peptide Letters 2005; 12 (1) . https://dx.doi.org/10.2174/0929866053405959
DOI https://dx.doi.org/10.2174/0929866053405959 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |
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