Abstract
Reports of cationic antimicrobial peptides (CAPs) have become standard fare in research literature. But with several hundred peptides described to date, the investigator who tries to navigate the proposed models of their activity is only treated to a generous serving of incongruencies. Rather than acting in isolation as antimicrobial molecules, CAPs also may synergize with other molecules of innate immunity and modulate both innate and adaptive immune systems, thus providing a link between the various mechanisms that result in host protection.
Keywords: antibiotic, biodiversity, cationic antimicrobial peptide, fish, genomics, microbicidal, synergy
Protein & Peptide Letters
Title: Antimicrobial Peptides: Cooperative Approaches to Protection
Volume: 12 Issue: 1
Author(s): Aleksander Patrzykat and Susan E. Douglas
Affiliation:
Keywords: antibiotic, biodiversity, cationic antimicrobial peptide, fish, genomics, microbicidal, synergy
Abstract: Reports of cationic antimicrobial peptides (CAPs) have become standard fare in research literature. But with several hundred peptides described to date, the investigator who tries to navigate the proposed models of their activity is only treated to a generous serving of incongruencies. Rather than acting in isolation as antimicrobial molecules, CAPs also may synergize with other molecules of innate immunity and modulate both innate and adaptive immune systems, thus providing a link between the various mechanisms that result in host protection.
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Cite this article as:
Patrzykat Aleksander and Douglas E. Susan, Antimicrobial Peptides: Cooperative Approaches to Protection, Protein & Peptide Letters 2005; 12 (1) . https://dx.doi.org/10.2174/0929866053406057
DOI https://dx.doi.org/10.2174/0929866053406057 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |
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