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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Reductive Amination of Carbonyl Compounds with NaBH4-H3PW12O40 in THF and Under Solvent-Free Conditions

Author(s): Heshmatollah Alinezhad and Ehsan Ardestani

Volume 4, Issue 7, 2007

Page: [473 - 477] Pages: 5

DOI: 10.2174/157017807782006254

Price: $65

Abstract

A simple, completely chemoselective, and convenient procedure for reductive amination of aldehydes and ketones using NaBH4 in the presence of H3PW12O40 in THF and under solvent-free conditions at ambient temperature is described.

Keywords: Reductive amination, H3PW12O40, NaBH4, solvent-free conditions


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