Synthesis of Ethyl 4-O-[4-(1,2,4-Oxadiazol-5-yl)phenyl]-α-D-mannopyranosides

Title: Synthesis of Ethyl 4-O-[4-(1,2,4-Oxadiazol-5-yl)phenyl]-α-D-mannopyranosides

Volume: 4 Issue: 6

Author(s): Janaina Versiani dos Anjos, Denis Sinou, Sebastiao Jose de Melo and Rajendra Mohan Srivastava

Affiliation:

Keywords: 1,2,4-Oxadiazole, palladium catalyst, ethyl α-O-Δ2-glycoside, ethyl mannopyranoside

Abstract: The palladium-catalyzed reaction of 5-(4-hydroxyphenyl)-1,2,4-oxadiazoles with ethyl α-O-Δ2-glucopyranoside afforded ethyl 4-O-[4-(1,2,4-oxadiazol-5-yl)phenyl]-2,3-dideoxy-α-D-erythro-hex-2-enopyranosides. Bishydroxylation of the latter compounds gave the corresponding ethyl 4-O-[4-(1,2,4-oxadiazol-5-yl)phenyl]-α-Dmannopyranosides.

Cite this article as:

Janaina Versiani dos Anjos , Denis Sinou , Sebastiao Jose de Melo and Rajendra Mohan Srivastava , Synthesis of Ethyl 4-O-[4-(1,2,4-Oxadiazol-5-yl)phenyl]-α-D-mannopyranosides, Letters in Organic Chemistry 2007; 4 (6) . https://dx.doi.org/10.2174/157017807781467579