Three-Component Synthesis of Dihydro-4-pyridones Catalyzed by Silica Sulfuric Acid

Title: Three-Component Synthesis of Dihydro-4-pyridones Catalyzed by Silica Sulfuric Acid

Volume: 4 Issue: 2

Author(s): Wei-Yi Chen and Xin-Sheng Li

Affiliation:

Keywords: Aza-Diels-Alder reaction, aldehyde, amine, Danishefsky's diene, dihydro-4-pyridone, silica sulfuric acid

Abstract: Three-component aza-Diels-Alder reactions of Danishefskys diene with aldehydes and amines took place smoothly to afford dihydro-4-pyridones with high yields in the presence of a catalytic amount of silica sulfuric acid (SSA). This new protocol consistently has the advantages of operational simplicity, economic consideration, and high yield.

Cite this article as:

Chen Wei-Yi and Li Xin-Sheng, Three-Component Synthesis of Dihydro-4-pyridones Catalyzed by Silica Sulfuric Acid, Letters in Organic Chemistry 2007; 4 (2) . https://dx.doi.org/10.2174/157017807780414082