A Facile Regioselective Synthesis of Tetracyclic Sulphur Heterocycles by Tandem Thio-Claisen Rearrangement (SUPPORTING DATA)

Title: A Facile Regioselective Synthesis of Tetracyclic Sulphur Heterocycles by Tandem Thio-Claisen Rearrangement (SUPPORTING DATA)

Volume: 4 Issue: 2

Author(s): Krishna C. Majumdar and Nilasish Pal

Affiliation:

Keywords: Thio-Claisen rearrangement, mercaptothiophene, regioselectivity, tetracyclic sulphur compounds, tandem cyclisation

Abstract: Thio-Claisen rearrangement of symmetrically substituted 1,4-but-2-ynes (3a,b and 4) exhibit tandem cyclization and afforded compounds 5a,b and 6 in good yields. These sulphides 3a,b and 4 were in turn prepared from commercially available thiophene. The key step in this transformation is tandem [3,3] sigmatropic rearrangement.

Cite this article as:

Majumdar C. Krishna and Pal Nilasish, A Facile Regioselective Synthesis of Tetracyclic Sulphur Heterocycles by Tandem Thio-Claisen Rearrangement (SUPPORTING DATA), Letters in Organic Chemistry 2007; 4 (2) . https://dx.doi.org/10.2174/157017807780414091