Abstract
Chiral derivative 3 has been recognized as a precursor of enantiopure 2,3-disubstituted piperidines. A study concerning the chemoselective reduction, using BH3.Me2S, of highly functionalised compounds 6 and N-BOC aminoacid 12 is reported.
Keywords: Asymmetric synthesis, pipecolic acids, piperidines, phenylglycinol, aza-annelation
Letters in Organic Chemistry
Title: Enantioselective Synthesis of 2,3-Disubstituted Piperidines
Volume: 4 Issue: 1
Author(s): Michael Calosso, Mathieu Wagner, Thomas Gendrineau, Morgane Petit, Catherine Kadouri-Puchot and Luc Dechoux
Affiliation:
Keywords: Asymmetric synthesis, pipecolic acids, piperidines, phenylglycinol, aza-annelation
Abstract: Chiral derivative 3 has been recognized as a precursor of enantiopure 2,3-disubstituted piperidines. A study concerning the chemoselective reduction, using BH3.Me2S, of highly functionalised compounds 6 and N-BOC aminoacid 12 is reported.
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Cite this article as:
Calosso Michael, Wagner Mathieu, Gendrineau Thomas, Petit Morgane, Kadouri-Puchot Catherine and Dechoux Luc, Enantioselective Synthesis of 2,3-Disubstituted Piperidines, Letters in Organic Chemistry 2007; 4 (1) . https://dx.doi.org/10.2174/157017807780037487
DOI https://dx.doi.org/10.2174/157017807780037487 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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