Generic placeholder image

Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

An Approach to Preparation of α-Hydroxyl Cyclobutanones from 1, 2-Bis(trimethylsiloxy)cyclobutene Catalyzed by MgI2 Etherate

Author(s): Xingxian Zhang

Volume 3, Issue 10, 2006

Page: [749 - 752] Pages: 4

DOI: 10.2174/157017806779025988

Price: $65

Abstract

We describe an efficient and practical preparation of α-hydroxyl cyclobutanones from 1,2- Bis(trimethylsiloxy)cyclobutene (BTCB) with aromatic aldehydes, α,β-unsaturated aldehydes and their parent acetals catalyzed by 1-5 mol% of MgI2 etherate (MgI2•(OEt2)n) in dichloromethane under mild reaction conditions in good yields.

Keywords: α-Hydroxyl cyclobutanone, aldehyde, acetal, 1,2-bis(trimethylsiloxy)cyclobutene, MgI2 etherate


Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy