Abstract
This review summarizes the knowledge of the role of dietary PUFAs, especially ω-3, on normal brain function. Furthermore, it reports the evidence pointing to potential mechanisms of ω-3 fatty acids in development of neurological disorders and efficacy of their supplementation in terms of symptom management.
Keywords: Docosahexaenoic acid, eicosapentaenoic acid, arachidonic acid, neurodegenerative diseases, Alzheimer's disease, Multiple sclerosis, Depression, Parkinson's disease
Mini-Reviews in Medicinal Chemistry
Title: Polyunsaturated Fatty Acids and Neurological Diseases
Volume: 6 Issue: 11
Author(s): S. Salvati, L. Attorri, R. Di Benedetto, A. Di Biase and F. Leonardi
Affiliation:
Keywords: Docosahexaenoic acid, eicosapentaenoic acid, arachidonic acid, neurodegenerative diseases, Alzheimer's disease, Multiple sclerosis, Depression, Parkinson's disease
Abstract: This review summarizes the knowledge of the role of dietary PUFAs, especially ω-3, on normal brain function. Furthermore, it reports the evidence pointing to potential mechanisms of ω-3 fatty acids in development of neurological disorders and efficacy of their supplementation in terms of symptom management.
Export Options
About this article
Cite this article as:
Salvati S., Attorri L., Di Benedetto R., Di Biase A. and Leonardi F., Polyunsaturated Fatty Acids and Neurological Diseases, Mini-Reviews in Medicinal Chemistry 2006; 6 (11) . https://dx.doi.org/10.2174/138955706778742740
DOI https://dx.doi.org/10.2174/138955706778742740 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
Call for Papers in Thematic Issues
Bioprospecting of Natural Products as Sources of New Multitarget Therapies
According to the Convention on Biological Diversity, bioprospecting is the exploration of biodiversity and indigenous knowledge to develop commercially valuable products for pharmaceutical and other applications. Bioprospecting involves searching for useful organic compounds in plants, fungi, marine organisms, and microorganisms. Natural products traditionally constituted the primary source of more than ...read more
Computational Frontiers in Medicinal Chemistry
The thematic issue "Computational Frontiers in Medicinal Chemistry" provides a robust platform for delving into state-of-the-art computational methodologies and technologies that significantly propel advancements in medicinal chemistry. This edition seeks to amalgamate top-tier reviews spotlighting the latest trends and breakthroughs in the fusion of computational approaches, including artificial intelligence (AI) ...read more
Natural Products and Dietary Supplements in Alleviation of Metabolic, Cardiovascular, and Neurological Disorders
Metabolic disorders like diabetes, obesity, inflammation, oxidative stress, cancer etc, cardiovascular disorders like angina, myocardial infarction, congestive heart failure etc as well as neurological disorders like Alzheimer?s, Parkinson?s, Epilepsy, Depression, etc are the global burden. They covered the major segment of the diseases and disorders from which the human community ...read more
Natural Products in Drug Discovery
Natural products have always been one of the important ways of drug discovery due to their novel skeleton and diverse functional group characteristics. According to statistics, between 1981 and 2019, the FDA approved a total of 1,394 small molecule drugs for marketing, of which 930 marketed drugs originated from the ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Stimulus-feature Specific Modulation of the Visual Processing by Audiovisual Intermodal Orientation of Attention
Neuroscience and Biomedical Engineering (Discontinued) Ajulemic Acid (CT3) A Potent Analog of the Acid Metabolites of THC
Current Pharmaceutical Design Antidepressants and Sleep: Neurophysiology and Clinical Correlates
Current Psychiatry Reviews Current Updates in Transdermal Therapeutic Systems and Their Role in Neurological Disorders
Current Protein & Peptide Science From Concept to Reality: The Long Road to c-Met and RON Receptor Tyrosine Kinase Inhibitors for the Treatment of Cancer
Anti-Cancer Agents in Medicinal Chemistry The Impact of Variable Factors on the Health-Related Quality of Life in the Elderly in Japan and Russia
Current Aging Science Predicting Monoamine Oxidase Inhibitory Activity Through Ligand-Based Models
Current Topics in Medicinal Chemistry Inhibition of the PERK-Dependent Unfolded Protein Response Signaling Pathway Involved in the Pathogenesis of Alzheimer’s Disease
Current Alzheimer Research Effectiveness of a Standardized and Specific Follow-Up in Memory Centers in Patients with Alzheimer’s Disease
Current Alzheimer Research New Insight into Diabetes Management: From Glycemic Index to Dietary Insulin Index
Current Diabetes Reviews Cardiovascular Tests: Use & Limits of Biochemical Markers - Therapeutic Measurements of ADMA Involved in Cardiovascular Disorders
Current Pharmaceutical Design Tumor Necrosis Factor-α, a Regulator and Therapeutic Agent on Breast Cancer
Current Pharmaceutical Biotechnology Expanding the Arsenal Against Huntington's Disease-Herbal Drugs and Their Nanoformulations
Current Neuropharmacology Voltage-gated Sodium Channels in Sensory Information Processing
CNS & Neurological Disorders - Drug Targets Dry Eyes in Rheumatic Disease
Current Rheumatology Reviews Editorial [Special Editorial Board Members Issue]
Mini-Reviews in Medicinal Chemistry The Risk that DSM-5 will Result in a Misallocation of Scarce Resources
Current Psychiatry Reviews Graphene Modified Molecular Imprinting Electrochemical Sensor for Determining the Content of Dopamine
Current Analytical Chemistry Cardiovascular and Metabolic Effects of Ghrelin
Current Diabetes Reviews MicroRNA-155 Regulates Inflammatory Response in Ischemic Cerebral Tissues through Autophagy
Current Neurovascular Research