Abstract
Oleoylethanolamide is an endogenous lipid mediator that reduces food intake and decreases body weight gain in rodents. As in leptin, oleoylethanolamide has a central and peripheral anorexic effect. In this article, we describe common potential targets, suggesting a molecular cross-talk between leptin and oleoylethanolamide which may regulate feeding behaviour.
Keywords: Oleoylethanolamide (OEA), Leptin, Obesity, Anorexigenic, Feeding behaviour, Anti-obesity effects, Rats
Letters in Drug Design & Discovery
Title: Oleoylethanolamide: a Molecular Cross-Talk with Leptin in Feeding Behaviour Regulation
Volume: 3 Issue: 10
Author(s): Buenaventura Brito, Rafael Castro and Antonio Cabrera de Leon
Affiliation:
Keywords: Oleoylethanolamide (OEA), Leptin, Obesity, Anorexigenic, Feeding behaviour, Anti-obesity effects, Rats
Abstract: Oleoylethanolamide is an endogenous lipid mediator that reduces food intake and decreases body weight gain in rodents. As in leptin, oleoylethanolamide has a central and peripheral anorexic effect. In this article, we describe common potential targets, suggesting a molecular cross-talk between leptin and oleoylethanolamide which may regulate feeding behaviour.
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Cite this article as:
Brito Buenaventura, Castro Rafael and Cabrera de Leon Antonio, Oleoylethanolamide: a Molecular Cross-Talk with Leptin in Feeding Behaviour Regulation, Letters in Drug Design & Discovery 2006; 3 (10) . https://dx.doi.org/10.2174/157018006778631901
DOI https://dx.doi.org/10.2174/157018006778631901 |
Print ISSN 1570-1808 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-628X |
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