Abstract
Solid organ transplantation was one of the greatest medical advances of the 20th century. Current preservation technology falls short of maintaining organs ex vivo in perpetuity. This review examines the biochemical basis of organ degradation in response to ischaemia, preservation solution composition and potential future organ preservation technology.
Keywords: Organ transplantation, preservation solutions, machine perfusion preservation, hypothermia
Mini-Reviews in Medicinal Chemistry
Title: Preservation Solutions for Solid Organ Transplantation
Volume: 6 Issue: 10
Author(s): C. H. Wilson, N. R. Brook and D. Talbot
Affiliation:
Keywords: Organ transplantation, preservation solutions, machine perfusion preservation, hypothermia
Abstract: Solid organ transplantation was one of the greatest medical advances of the 20th century. Current preservation technology falls short of maintaining organs ex vivo in perpetuity. This review examines the biochemical basis of organ degradation in response to ischaemia, preservation solution composition and potential future organ preservation technology.
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Cite this article as:
H. Wilson C., R. Brook N. and Talbot D., Preservation Solutions for Solid Organ Transplantation, Mini-Reviews in Medicinal Chemistry 2006; 6 (10) . https://dx.doi.org/10.2174/138955706778560148
DOI https://dx.doi.org/10.2174/138955706778560148 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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