Abstract
A novel and convenient synthetic approach to ubiquinone-10 was reported via the SN2-type nucleophilic displacement reaction between copper-catalyzed Grignard reagent and the secondary allylic acetate, which was suitable for the large-scale production of ubiquinone-10.
Keywords: SN2'-type reaction, copper-catalyzed, Grignard reagent, secondary allylic acetate, regioselectivity, stereoselectivity
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