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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Clean and Facile Condensations Reaction of Indoles and Carbonyl Compounds Under Solvent-Free Conditions

Author(s): Shokoufeh Mehrazma, Najmoddin Azizi and Mohammad R. Saidi

Volume 3, Issue 2, 2006

Page: [161 - 164] Pages: 4

DOI: 10.2174/157017806775224251

Price: $65

Abstract

A simple, rapid, atom economy and highly efficient green protocol has been developed for the reactions of indole with carbonyl compounds under solvent- free conditions. The attractive features of these procedures are the mild reaction conditions, high conversions, cleaner reaction profiles, inexpensive and environmentally friendly lithium perchlorate and short reaction times.

Keywords: indole, bis indole, carbonyl compounds, lithium perchlorate, atom economy


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