Abstract
Genetic engineering is a powerful technique to create genetic modifications for desirable trait and is the purposeful transfer and integration of a foreign gene to the genome of an organism. Gene holds information that gives the organism a particular trait and can be transferred from one organism to another. Safe and efficient DNA delivery is the most important requisite in biological research. There are many methods used for gene transfer but all have certain drawbacks, as nanoparticles are small in size, can penetrate the cell and deliver drugs or biomolecules such as protein into the living systems and can be used as transgenic vehicle for nucleic acid. The present review focuses on nanoparticles, which can act as transgenic vehicle for nucleic acids (DNA, RNA and oligonucleotides) in cell and their comparison with different methods used for genetic material transfer.
Keywords: Gene delivery, Functionalized nanoparticles, Nanotube, Transgenic vehicle, Transfection, Transformation, Genetic engineering, nucleic acid
Call for Papers in Thematic Issues
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The application of nanoscience has brought about a revolution in the field of mechanical engineering by providing novel materials, boosting manufacturing processes, and generating cutting-edge products. The purpose of this special issue is to investigate the enormous impact that nanoscience has had on mechanical engineering, with a particular emphasis on ...read more
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This special issue collection will highlight developments on the recent trends about the synthesis of metal oxides, nanoclusters, biomaterials, 2D nanomaterials, nanocrystals, nanocomposites, etc. and their applications in electrochemical systems, tissue regeneration, energy storage and harvesting, sensors, etc. The novelty of the methods in the chemical synthesis and their characterizations, ...read more
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