Abstract
There has been considerable interest in the development of novel compounds with anticonvulsant, antioxidant, hormone antagonist, analgesic, anti-inflammatory, antiplatelet, antimalarial, antimicrobial, antimycobacterial, antitumoral, vasodilator, antiviral and anti-trypanosomal activities. Hydrazones possessing an azometine -NHN=CH- proton constitute an important class of compounds for new drug development. Therefore, many researchers have synthesized these compounds as target structures and evaluated their biological activities. These observations have been guiding for the development of new hydrazide derivatives that possess varied biological activities.
Keywords: Biological activities, Antimicrobial, Antiviral, Antimycobacterial, Anti-inflammatory, Analgesic, Antioxidant, Anticancer, Antimalarial, Antiarthritis, Anti-trypnosomal, Diuretic, Hydrazide, Hydrazone, Synthesis
Current Medicinal Chemistry
Title: A Review on Biological Activities and Chemical Synthesis of Hydrazide Derivatives
Volume: 19 Issue: 4
Author(s): R. Narang, B. Narasimhan and S. Sharma
Affiliation:
Keywords: Biological activities, Antimicrobial, Antiviral, Antimycobacterial, Anti-inflammatory, Analgesic, Antioxidant, Anticancer, Antimalarial, Antiarthritis, Anti-trypnosomal, Diuretic, Hydrazide, Hydrazone, Synthesis
Abstract: There has been considerable interest in the development of novel compounds with anticonvulsant, antioxidant, hormone antagonist, analgesic, anti-inflammatory, antiplatelet, antimalarial, antimicrobial, antimycobacterial, antitumoral, vasodilator, antiviral and anti-trypanosomal activities. Hydrazones possessing an azometine -NHN=CH- proton constitute an important class of compounds for new drug development. Therefore, many researchers have synthesized these compounds as target structures and evaluated their biological activities. These observations have been guiding for the development of new hydrazide derivatives that possess varied biological activities.
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Cite this article as:
Narang R., Narasimhan B. and Sharma S., A Review on Biological Activities and Chemical Synthesis of Hydrazide Derivatives, Current Medicinal Chemistry 2012; 19 (4) . https://dx.doi.org/10.2174/092986712798918789
DOI https://dx.doi.org/10.2174/092986712798918789 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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