Abstract
Asymmetric Mannich-type reactions are important organic transformations that provide excellent protocols for the synthesis of optically active nitrogen-containing compounds. This article provides an overview on the development of thiourea-catalyzed asymmetric Mannich or nitro-Mannich reactions including scope, limitations, and applications of different catalytic systems.
Keywords: Thiourea, Mannich-type reaction, asymmetric catalysis, organocatalysis, organocatalytic, organic chemistry, stereoselective catalysis, hydrogen-bonding donors, monothiourea, bis-thiourea, b-amino acids, Lewis basic, Isoquinolines, Wittig Reaction, Nitro-Mannich
Current Organic Chemistry
Title: Thiourea-Catalyzed Asymmetric Mannich-Type Reactions
Volume: 15 Issue: 24
Author(s): Bo Han, Jun-Long Li, You-Cai Xiao, Si-Li Zhou and Ying-Chun Chen
Affiliation:
Keywords: Thiourea, Mannich-type reaction, asymmetric catalysis, organocatalysis, organocatalytic, organic chemistry, stereoselective catalysis, hydrogen-bonding donors, monothiourea, bis-thiourea, b-amino acids, Lewis basic, Isoquinolines, Wittig Reaction, Nitro-Mannich
Abstract: Asymmetric Mannich-type reactions are important organic transformations that provide excellent protocols for the synthesis of optically active nitrogen-containing compounds. This article provides an overview on the development of thiourea-catalyzed asymmetric Mannich or nitro-Mannich reactions including scope, limitations, and applications of different catalytic systems.
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Cite this article as:
Han Bo, Li Jun-Long, Xiao You-Cai, Zhou Si-Li and Chen Ying-Chun, Thiourea-Catalyzed Asymmetric Mannich-Type Reactions, Current Organic Chemistry 2011; 15 (24) . https://dx.doi.org/10.2174/138527211798109204
DOI https://dx.doi.org/10.2174/138527211798109204 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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