Abstract
Studies have shown that breast conserving surgery is as efficacious as mastectomy in the treatment of women with early stage breast cancer. Recent publications, however, have demonstrated an increasing number of women electing bilateral mastectomy when diagnosed with unilateral breast cancer. Several plausible reasons for this rising trend for bilateral mastectomy include increased awareness of breast cancer risk in the contralateral breast, increased use of breast MRI as a diagnostic tool and advances in reconstructive and mastectomy techniques. This review will focus mainly on the reconstructive options within the third probable reason for the increasing trend of bilateral mastectomy, advances in breast reconstruction and mastectomy techniques. The various options in breast reconstruction will be presented with a historical perspective, as well as a brief discussion on current mastectomy techniques in breast surgical oncology, as advances in both fields have likely influenced the rising trend of bilateral mastectomy in the United States.
Keywords: Prophylactic mastectomy, breast reconstruction, implant reconstruction, autologous reconstruction, historical review
Current Cancer Therapy Reviews
Title: Breast Reconstruction – A Historical Perspective on Available Techniques for Patients Electing Bilateral Mastectomy
Volume: 7 Issue: 4
Author(s): Jonas A. Nelson, Julia Tchou, Susan Domchek, David W. Low, Joseph M. Serletti and Liza C. Wu
Affiliation:
Keywords: Prophylactic mastectomy, breast reconstruction, implant reconstruction, autologous reconstruction, historical review
Abstract: Studies have shown that breast conserving surgery is as efficacious as mastectomy in the treatment of women with early stage breast cancer. Recent publications, however, have demonstrated an increasing number of women electing bilateral mastectomy when diagnosed with unilateral breast cancer. Several plausible reasons for this rising trend for bilateral mastectomy include increased awareness of breast cancer risk in the contralateral breast, increased use of breast MRI as a diagnostic tool and advances in reconstructive and mastectomy techniques. This review will focus mainly on the reconstructive options within the third probable reason for the increasing trend of bilateral mastectomy, advances in breast reconstruction and mastectomy techniques. The various options in breast reconstruction will be presented with a historical perspective, as well as a brief discussion on current mastectomy techniques in breast surgical oncology, as advances in both fields have likely influenced the rising trend of bilateral mastectomy in the United States.
Export Options
About this article
Cite this article as:
A. Nelson Jonas, Tchou Julia, Domchek Susan, W. Low David, M. Serletti Joseph and C. Wu Liza, Breast Reconstruction – A Historical Perspective on Available Techniques for Patients Electing Bilateral Mastectomy, Current Cancer Therapy Reviews 2011; 7 (4) . https://dx.doi.org/10.2174/157339411797642579
DOI https://dx.doi.org/10.2174/157339411797642579 |
Print ISSN 1573-3947 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6301 |
Call for Papers in Thematic Issues
Current progress in Protein Degradation and Cancer Therapy
argeted Protein Degradation is gaining momentum in cancer therapy, it facilitate targeting undruggable proteins, it overcome cancer resistance and avoid undesirable side effects. Thus small molecules degraders have emerged as novel therapeutic strategy. Targeted protein degradation (TPD), the process of eliminating a protein of interest hold a great promise for ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Molecular Dynamics and Biological Evaluation of 2-chloro-7-cyclopentyl- 7H-pyrrolo[2,3-d]pyrimidine Derivatives Against Breast Cancer
Combinatorial Chemistry & High Throughput Screening Radiolabeled Peptides for SPECT and PET Imaging in the Detection of Breast Cancer: Preclinical and Clinical Perspectives
Current Medicinal Chemistry Polyketide Natural Products, Acetogenins from Graviola (Annona muricata L), its Biochemical, Cytotoxic Activity and Various Analyses Through Computational and Bio-Programming Methods
Current Pharmaceutical Design G-Lymphatic, Vascular and Immune Pathways for Aβ Clearance Cascade and Therapeutic Targets For Alzheimer’s Disease
Combinatorial Chemistry & High Throughput Screening FOXM1 and its Oncogenic Signaling in Gastric Cancer
Recent Patents on Anti-Cancer Drug Discovery p53 Activation by Blocking Snail : A Novel Pharmacological Strategy for Cancer
Current Pharmaceutical Design Targeting the p53-Family in Cancer and Chemosensitivity: Triple Threat
Current Drug Targets Application of Serial Analysis of Gene Expression in Cancer Research
Current Pharmaceutical Biotechnology Is there Any Correlation Between Binding and Functional Effects at the Translocator Protein (TSPO) (18 kDa)?
Current Molecular Medicine N6-methyladenine RNA Modification (m<sup>6</sup>A): An Emerging Regulator of Metabolic Diseases
Current Drug Targets Can we Target the Chemokine Network for Cancer Therapeutics?
Current Cancer Drug Targets Neurotransmitters and Chemokines Regulate Tumor Cell Migration: Potential for a New Pharmacological Approach to Inhibit Invasion and Metastasis Development
Current Pharmaceutical Design Molecules from Nature: Modulating the Expression of Estrogen Receptor Genes in Breast Cancer Cells
Current Bioactive Compounds Dendritic Cell Immunotherapy for Melanoma
Reviews on Recent Clinical Trials Medical Therapy and Mucosal Healing
Current Drug Targets The Vitamin D/CYP24A1 Story in Cancer
Anti-Cancer Agents in Medicinal Chemistry Subject Index to Volume 4
Current Drug Metabolism Novel Resveratrol-chalcone Derivatives: Synthesis and Biological Evaluation
Mini-Reviews in Medicinal Chemistry Role of Vitamins in Human Health and Nutrition: Sources and Morbidity
Current Nutrition & Food Science Piperine: Medicinal, Analytical and Therapeutics perspective
Current Bioactive Compounds