Abstract
Herein we give a brief account of the efforts our group made in recent years to discover novel enzymes and utilize them by bioprocess engineering techniques for stereoselective synthesis of various enantiomerically pure chiral chemicals with high value in a greener manner. Included are discussions on oxidoreductases, expoxide hydrolases and glucosidases in whole cells or isolated form from microorganisms or plants.
Keywords: Target-directed discovery, Biocatalysis, Oxidoreductases, Expoxide hydrolases, Glucosidases, Bioprocess engineering, Reductases, Rhodotorula sp. AS2.2241, Bacillus sp. ECU0013, Adzuki Bean Ketone Reductases, Pseudomonas putida ECU1009, Glycolate Oxidase, Alcaligenes sp. ECU0401, Rhodococcus sp. ECU0066, EPOXIDE HYDROLASES
Current Organic Chemistry
Title: Target-directed Discovery and Bioprocess Engineering of New Enzymes for Environmentally Benign Production of High-Value Chiral Chemicals
Volume: 15 Issue: 14
Author(s): Ling Ou, Hui-Lei Yu and Jian-He Xu
Affiliation:
Keywords: Target-directed discovery, Biocatalysis, Oxidoreductases, Expoxide hydrolases, Glucosidases, Bioprocess engineering, Reductases, Rhodotorula sp. AS2.2241, Bacillus sp. ECU0013, Adzuki Bean Ketone Reductases, Pseudomonas putida ECU1009, Glycolate Oxidase, Alcaligenes sp. ECU0401, Rhodococcus sp. ECU0066, EPOXIDE HYDROLASES
Abstract: Herein we give a brief account of the efforts our group made in recent years to discover novel enzymes and utilize them by bioprocess engineering techniques for stereoselective synthesis of various enantiomerically pure chiral chemicals with high value in a greener manner. Included are discussions on oxidoreductases, expoxide hydrolases and glucosidases in whole cells or isolated form from microorganisms or plants.
Export Options
About this article
Cite this article as:
Ou Ling, Yu Hui-Lei and Xu Jian-He, Target-directed Discovery and Bioprocess Engineering of New Enzymes for Environmentally Benign Production of High-Value Chiral Chemicals, Current Organic Chemistry 2011; 15 (14) . https://dx.doi.org/10.2174/138527211796150598
DOI https://dx.doi.org/10.2174/138527211796150598 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
Call for Papers in Thematic Issues
Advances of Heterocyclic Chemistry with Pesticide Activity
Global food safety and security will continue to be a global concern for the next 50 years and beyond. Plant diseases have had a significant impact on food safety and security throughout the entire food chain, from primary production to consumption. While conventional chemical pesticides have been traditionally used for ...read more
Calculation design of covalent/metal organic framework based catalysts
This research area combines theoretical computation and screening with machine learning for the design of covalent/metal organic framework-based catalysts, bridging the disciplines of organic chemistry, physical chemistry, computational chemistry, materials science, and machine learning. It covers several critical aspects: designing and synthesizing organic catalysts for improved performance, applying computational methods ...read more
Carbohydrates conversion in biofuels and bioproducts
Biomass pretreatment, hydrolysis, and saccharification of carbohydrates, and sugars bioconversion in biofuels and bioproducts within a biorefinery framework. Carbohydrates derived from woody biomass, agricultural wastes, algae, sewage sludge, or any other lignocellulosic feedstock are included in this issue. Simulation, techno-economic analysis, and life cycle analysis of a biorefinery process are ...read more
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
The Linkage Between Inflammation and Immune Tolerance: Interfering with Inflammation in Cancer
Current Cancer Drug Targets Inflammatory Biomarkers, Depressive Symptoms and Falls Among the elderly in Panama
Current Aging Science Cannabinoid Drugs and Enhancement of Endocannabinoid Responses: Strategies for a Wide Array of Disease States
Current Molecular Medicine Effective Use of Drugs to Counter Chemical Terrorism
Current Drug Therapy Theory of Mind is Just Behavior
Current Psychiatry Reviews Use of Atypical Antipsychotics as Mono/Polytherapy with Mood Stabilizers for the Treatment of Bipolar Disorder. An Update
Current Psychopharmacology Cardiovascular Biology of Interleukin-6
Current Pharmaceutical Design Clioquinol – A Novel Copper-Dependent and Independent Proteasome Inhibitor
Current Cancer Drug Targets Physical Properties of ZnO: Al Nanorods for Piezoelectric Nanogenerator Application
Current Nanoscience Editorial: US Students Alcohol Consumption: A Downward Trend, But Increased Concerns
Current Drug Abuse Reviews Immunomodulation in Inflammatory Neuropathies: Rationale and Safety
Current Drug Safety Involvement of Rat Hippocampal Astrocytes in β-Amyloid-Induced Angiogenesis and Neuroinflammation
Current Alzheimer Research A Review of Clinical Pharmacokinetics and Pharmacodynamics of Galantamine, a Reversible Acetylcholinesterase Inhibitor for the Treatment of Alzheimer s Disease, in Healthy Subjects and Patients
Current Clinical Pharmacology Phenolic Compounds: the Role of Redox Regulation in Neurodegenerative Disease and Cancer
Mini-Reviews in Medicinal Chemistry Human Tooth Germ Stem Cells Preserve Neuro-Protective Effects after Long-Term Cryo-Preservation
Current Neurovascular Research Bibliometrics and Visualization of the Mechanisms of Parkinson's Diseases Based on Animal Models
Endocrine, Metabolic & Immune Disorders - Drug Targets Vitamins in the Prevention or Delay of Cognitive Disability of Aging
Current Aging Science Natural Products as Potential Anti-Alzheimer Agents
Current Medicinal Chemistry Ethical Issues in Managing the Pregnancies of Patients with Schizophrenia
Current Women`s Health Reviews Innate Immune System Modulation During Aging: Contributions of Macrophages and Dendritic Cells
Current Immunology Reviews (Discontinued)