Abstract
In our analysis, patients who were treated with intravenous rt-PA had a better outcome than untreated patients, and this effect was not dependent on age. The weight of evidence to date indicates a potential for benefit in older people, and there is no a priori reason to suspect a diminished effect when compared with younger people. The risk of bleeding is similar in both groups. We believe that clinical treatment guidelines should be revised in order to remove the age restriction in the use of intravenous rt-PA acute ischemic stroke.
Keywords: NINDS rt-PA, INTRACRANIAL BLEEDING, octogenarians, rt-PA, elderly, thrombolysis, Acute ischemic stroke
Cardiovascular & Hematological Disorders-Drug Targets
Title: Acute Management in Very Old Patients: Is Thrombolysis Safe?
Volume: 11 Issue: 1
Author(s): Fabiana Ortega and Maria C. Zurru
Affiliation:
Keywords: NINDS rt-PA, INTRACRANIAL BLEEDING, octogenarians, rt-PA, elderly, thrombolysis, Acute ischemic stroke
Abstract: In our analysis, patients who were treated with intravenous rt-PA had a better outcome than untreated patients, and this effect was not dependent on age. The weight of evidence to date indicates a potential for benefit in older people, and there is no a priori reason to suspect a diminished effect when compared with younger people. The risk of bleeding is similar in both groups. We believe that clinical treatment guidelines should be revised in order to remove the age restriction in the use of intravenous rt-PA acute ischemic stroke.
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Cite this article as:
Ortega Fabiana and C. Zurru Maria, Acute Management in Very Old Patients: Is Thrombolysis Safe?, Cardiovascular & Hematological Disorders-Drug Targets 2011; 11 (1) . https://dx.doi.org/10.2174/187152911795945204
DOI https://dx.doi.org/10.2174/187152911795945204 |
Print ISSN 1871-529X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-4063 |
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