Abstract
Magnetite (Fe3O4), is an extensively studied material because of several interesting properties and associated applications. However, synthesizing functional magnetite nano- and microstructures as ferrofluids for use in biomedical field still remains a challenge due to the technical limitations associated with the fabrication process. We have developed a one-step, low energy consumable process for the synthesis of highly monodisperse magnetite nanoparticles using thioglycerol as a stabilizing agent. The characterization of synthesized nanoparticles has been carried out using particle size analyzer, Transmission electron microscopy (TEM), X-ray diffractometry (XRD) and Fourier transform infrared spectrometry (FTIR). The antibacterial property of the synthesized magnetite nanoparticles has also been investigated and the results indicated that the tested pathogenic microorganisms are quite susceptible to very low concentrations of thioglycerol stabilized magnetite nanoparticles (TSMNs). The minimum inhibitory concentrations of synthesized TSMNs were found to be 0.041 mg/ml for E. coli and 0.047mg/ml for Staphylococcus aureus, Bacillus subtilis and Pseudomonas aeruginosa. Such antibacterial properties pose great promise for nanomaterials stabilized with organic molecules to be used in bio-medical applications.
Keywords: Antibacterial activity, magnetite, MIC, nanoparticles, stabilization, thioglycerol, Fe3O4, TEM, XRD, FTIR, NCIM, ATCC, MHA, KBr, JCPDS, DLS, Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis, Escherischia coli, SH group, antibiotics, Gram-positive, Gram-negative, NEERI
Current Nanoscience
Title: Synthesis and Broad Spectrum Antibacterial Activity of Magnetite Ferrofluid
Volume: 6 Issue: 6
Author(s): Charusheela Ramteke, Bijaya Ketan Sarangi, Tapan Chakrabarti, Sandeep Mudliar, Dewanand Satpute and Ram Avatar Pandey
Affiliation:
Keywords: Antibacterial activity, magnetite, MIC, nanoparticles, stabilization, thioglycerol, Fe3O4, TEM, XRD, FTIR, NCIM, ATCC, MHA, KBr, JCPDS, DLS, Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis, Escherischia coli, SH group, antibiotics, Gram-positive, Gram-negative, NEERI
Abstract: Magnetite (Fe3O4), is an extensively studied material because of several interesting properties and associated applications. However, synthesizing functional magnetite nano- and microstructures as ferrofluids for use in biomedical field still remains a challenge due to the technical limitations associated with the fabrication process. We have developed a one-step, low energy consumable process for the synthesis of highly monodisperse magnetite nanoparticles using thioglycerol as a stabilizing agent. The characterization of synthesized nanoparticles has been carried out using particle size analyzer, Transmission electron microscopy (TEM), X-ray diffractometry (XRD) and Fourier transform infrared spectrometry (FTIR). The antibacterial property of the synthesized magnetite nanoparticles has also been investigated and the results indicated that the tested pathogenic microorganisms are quite susceptible to very low concentrations of thioglycerol stabilized magnetite nanoparticles (TSMNs). The minimum inhibitory concentrations of synthesized TSMNs were found to be 0.041 mg/ml for E. coli and 0.047mg/ml for Staphylococcus aureus, Bacillus subtilis and Pseudomonas aeruginosa. Such antibacterial properties pose great promise for nanomaterials stabilized with organic molecules to be used in bio-medical applications.
Export Options
About this article
Cite this article as:
Ramteke Charusheela, Ketan Sarangi Bijaya, Chakrabarti Tapan, Mudliar Sandeep, Satpute Dewanand and Avatar Pandey Ram, Synthesis and Broad Spectrum Antibacterial Activity of Magnetite Ferrofluid, Current Nanoscience 2010; 6 (6) . https://dx.doi.org/10.2174/157341310793348605
DOI https://dx.doi.org/10.2174/157341310793348605 |
Print ISSN 1573-4137 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6786 |
Call for Papers in Thematic Issues
Role of nanomaterials in fabrication of coatings, Machining and Joining
The application of nanoscience has brought about a revolution in the field of mechanical engineering by providing novel materials, boosting manufacturing processes, and generating cutting-edge products. The purpose of this special issue is to investigate the enormous impact that nanoscience has had on mechanical engineering, with a particular emphasis on ...read more
Advanced Inorganic Nanocomposites and Their Emerging Applications
This special issue collection will highlight developments on the recent trends about the synthesis of metal oxides, nanoclusters, biomaterials, 2D nanomaterials, nanocrystals, nanocomposites, etc. and their applications in electrochemical systems, tissue regeneration, energy storage and harvesting, sensors, etc. The novelty of the methods in the chemical synthesis and their characterizations, ...read more
Applicability of Nanotechnology for Performance Enhancement of Clean Energy Technologies
Population growth, industrialization, and improvement in living quality would lead to further increase in energy demand in near future. Regarding the disadvantages of fossil fuels such as fluctuations in their price, high emissions of greenhouse gases and restriction of their sources, it is crucial to use and exploit alternative energy ...read more
Graphene and 2D Materials for Energy Storage and Conversion
This thematic issue will discuss the recent advances in graphene-based nanomaterials for different energy technologies. Graphene possesses a high surface area, and stable structure and exhibits many interesting electronic, optical, and mechanical properties due to its 2D crystal structure. Graphene is of both fundamental interest and suitable for a wide ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Senescence and Cell Death Pathways and Their Role in Cancer Therapeutic Outcome
Current Medicinal Chemistry Schizophrenia: A Systematic Review of the Disease State, Current Therapeutics and their Molecular Mechanisms of Action
Current Medicinal Chemistry Docosahexaenoic Acid (DHA) Sensitizes Brain Tumor Cells to Etoposide-Induced Apoptosis
Current Molecular Medicine Cancer Gene Therapy through Autonomous Parvovirus - Mediated Gene Transfer
Current Gene Therapy Ginsenoside Rh2 Inhibits Migration of Lung Cancer Cells under Hypoxia via mir-491
Anti-Cancer Agents in Medicinal Chemistry Meet Our Editorial Board Member
Current Drug Discovery Technologies Current Evidence and Potential Mechanisms of Therapeutic Action of PEDF in Cervical Cancer Treatment
Current Molecular Medicine Sialic Acid and the Central Nervous System: Perspectives on Biological Functions, Detection, Imaging Methods and Manipulation
CNS & Neurological Disorders - Drug Targets Regulation of Mitochondrial Function and its Impact in Metabolic Stress
Current Medicinal Chemistry Inhibition of Angiogenesis as a Treatment Strategy for Neuroblastoma
Current Cancer Therapy Reviews Ultrasmall Nanoclusters: Synthesis and Applications as an Emerging Platform for Imaging and Therapy
Current Analytical Chemistry Endothelial Colony Forming Capacity is Related to C-Reactive Protein Levels in Healthy Subjects
Current Neurovascular Research MicroRNA-7 Regulates Insulin Signaling Pathway by Targeting IRS1, IRS2, and RAF1 Genes in Gestational Diabetes Mellitus
MicroRNA Patent Selections
Recent Patents on Biomarkers Biological Modulation by Lectins and Their Ligands in Tumor Progression and Metastasis
Anti-Cancer Agents in Medicinal Chemistry Gene Therapy Based on Lipid Nanoparticles as Non-viral Vectors for Glioma Treatment
Current Gene Therapy Flavonoids and other Non-alkaloidal Constituents of Genus Erythrina: Phytochemical Review
Combinatorial Chemistry & High Throughput Screening Review of the Contribution of Radiolabelled Tracers for Tumour Cell Status Imaging
Current Medical Imaging Gene Expression Studies in Multiple Sclerosis
Current Genomics Poly(Ethylene Glycol) Amphiphilic Copolymer for Anticancer Drugs Delivery
Anti-Cancer Agents in Medicinal Chemistry